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STEP-BY-STEP diagnosis of cardiac amyloidosis: from suspicion to verification

https://doi.org/10.51922/2616-633X.2024.8.2.2328

Abstract

The article analyzes the modern view on the algorithm for the diagnosis of amyloid cardiomyopathy and the role of cardiovascular magnetic resonance imaging in it. A step-by-step diagnosis of AA amyloidosis of the heart is presented using a clinical case as an example. The course of the disease was characterized by worsening of the symptoms of heart failure in combination with persistent increase in troponin levels, pseudo-infarction pattern on the electrocardiogram, and unexplained myocardial hypertrophy according to echocardiography. In order to clarify the nature of the myocardial damage, a cardiovascular MRI was performed, the results of which revealed signs of storage disease. In order to confirm amyloidosis, a histological examination of a biopsy of the oral mucosa was performed.

About the Authors

A. A. Bondareva
City Clinical Hospital of Emergency Medical Care
Belarus

 Minsk 



E. M. Balysh
Belarusian State Medical University
Belarus

 Minsk 



T. V. Statkevich
Belarusian State Medical University
Belarus

 Minsk  Minsk 



E. B. Petrova
Belarusian State Medical University
Belarus

 Minsk 



O. M. Shabunevich
City Clinical Hospital of Emergency Medical Care
Belarus

 Minsk 



D. S. Moiseenko
City Clinical Hospital of Emergency Medical Care
Belarus

 Minsk 



N. B. Kononchuk
Belarusian State Medical University
Belarus

 Minsk 



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For citations:


Bondareva A.A., Balysh E.M., Statkevich T.V., Petrova E.B., Shabunevich O.M., Moiseenko D.S., Kononchuk N.B. STEP-BY-STEP diagnosis of cardiac amyloidosis: from suspicion to verification. Emergency Cardiology and Cardiovascular Risks journal. 2024;8(2):2328–2336. (In Russ.) https://doi.org/10.51922/2616-633X.2024.8.2.2328

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