Lamin-related dilated cardiomyopathy
https://doi.org/10.51922/2616-633X.2025.9.1.2483
Abstract
Lamin-related dilated cardiomyopathy is a genetic disease that causes rapidly progressive heart failure (HF), various arrhythmias and conduction disorders, and it is associated with a high risk of sudden cardiac death (SCD). The article presents a clinical case of a patient with cardiomyo- pathy caused by mutations in the LMNA gene, its early manifestations being rapidly progressive HF, ventricular systolic dysfunction, valvular abnormalities, supraventricular and ventricular rhythm and conduction disorders. The case study shows the evolution of clinical manifestations during the follow-up period, as well as discusses the risk stratification of sudden cardiac death and the strategy of its prevention.
About the Authors
S. M. Komissarova
State Institution Republican Scientific and Practical Centre “Cardiology”
Belarus
Belarus
220036, R. Luxemburg 110, Minsk
N. M. Rineiska
State Institution Republican Scientific and Practical Centre “Cardiology”
Belarus
Belarus
220036, R. Luxemburg 110, Minsk
N. N. Chakova
Institute of Genetics and Cytology of Belarus National Academy of Sciences
Belarus
Belarus
220072, Akademicheskaya 27, Minsk
S. S. Niyazova
Institute of Genetics and Cytology of Belarus National Academy of Sciences
Belarus
Belarus
220072, Akademicheskaya 27, Minsk
A. Yu. Dubovik
State Institution Republican Scientific and Practical Centre “Cardiology”
Belarus
Belarus
220036, R. Luxemburg 110, Minsk
A. A. Efimova
State Institution Republican Scientific and Practical Centre “Cardiology”
Belarus
Belarus
220036, R. Luxemburg 110, Minsk
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Review
For citations:
Komissarova S.M., Rineiska N.M., Chakova N.N., Niyazova S.S., Dubovik A.Yu., Efimova A.A. Lamin-related dilated cardiomyopathy. Emergency Cardiology and Cardiovascular Risks journal. 2025;9(1):2483-2490. (In Russ.) https://doi.org/10.51922/2616-633X.2025.9.1.2483
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